EGFR inhibition promotes an aggressive invasion pattern mediated by mesenchymal-like tumor cells within squamous cell carcinomas. [electronic resource]
Producer: 20140519Description: 2176-86 p. digitalISSN:- 1538-8514
- Antibodies, Monoclonal, Humanized -- administration & dosage
- Cadherins -- genetics
- Carcinoma, Squamous Cell -- drug therapy
- Cell Line, Tumor
- Cell Lineage
- Cetuximab
- Epithelial-Mesenchymal Transition -- genetics
- ErbB Receptors -- antagonists & inhibitors
- Erlotinib Hydrochloride
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Mesoderm -- cytology
- Neoplasm Invasiveness -- genetics
- Quinazolines -- administration & dosage
- Spheroids, Cellular -- cytology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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