EGFR inhibition promotes an aggressive invasion pattern mediated by mesenchymal-like tumor cells within squamous cell carcinomas.
Basu, Devraj
EGFR inhibition promotes an aggressive invasion pattern mediated by mesenchymal-like tumor cells within squamous cell carcinomas. [electronic resource] - Molecular cancer therapeutics Oct 2013 - 2176-86 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1538-8514
10.1158/1535-7163.MCT-12-1210 doi
Antibodies, Monoclonal, Humanized--administration & dosage
Cadherins--genetics
Carcinoma, Squamous Cell--drug therapy
Cell Line, Tumor
Cell Lineage
Cetuximab
Epithelial-Mesenchymal Transition--genetics
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride
Gene Expression Regulation, Neoplastic--drug effects
Humans
Mesoderm--cytology
Neoplasm Invasiveness--genetics
Quinazolines--administration & dosage
Spheroids, Cellular--cytology
Xenograft Model Antitumor Assays
EGFR inhibition promotes an aggressive invasion pattern mediated by mesenchymal-like tumor cells within squamous cell carcinomas. [electronic resource] - Molecular cancer therapeutics Oct 2013 - 2176-86 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1538-8514
10.1158/1535-7163.MCT-12-1210 doi
Antibodies, Monoclonal, Humanized--administration & dosage
Cadherins--genetics
Carcinoma, Squamous Cell--drug therapy
Cell Line, Tumor
Cell Lineage
Cetuximab
Epithelial-Mesenchymal Transition--genetics
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride
Gene Expression Regulation, Neoplastic--drug effects
Humans
Mesoderm--cytology
Neoplasm Invasiveness--genetics
Quinazolines--administration & dosage
Spheroids, Cellular--cytology
Xenograft Model Antitumor Assays