The relative expression of Mig6 and EGFR is associated with resistance to EGFR kinase inhibitors. [electronic resource]
Producer: 20140421Description: e68966 p. digitalISSN:- 1932-6203
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- ErbB Receptors -- antagonists & inhibitors
- Erlotinib Hydrochloride
- Female
- Gefitinib
- Humans
- Immunoblotting
- Kaplan-Meier Estimate
- Lung -- drug effects
- Lung Neoplasms -- drug therapy
- Male
- Mice
- Middle Aged
- Phosphatidylinositol 3-Kinases -- metabolism
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- Quinazolines -- pharmacology
- RNA Interference
- Signal Transduction -- drug effects
- Tumor Suppressor Proteins -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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