Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-β receptor I internalization and inhibiting transforming growth factor-β1 signaling. [electronic resource]
Producer: 20131126Description: 831-41 p. digitalISSN:- 1535-4970
- Animals
- Apoptosis
- Bleomycin -- administration & dosage
- Bronchoalveolar Lavage
- Caveolin 1 -- drug effects
- Disease Models, Animal
- Gene Expression Profiling
- Genetic Markers
- Humans
- Hydroxyproline -- analysis
- Idiopathic Pulmonary Fibrosis -- chemically induced
- In Vitro Techniques
- Macrophages, Alveolar -- drug effects
- Mice
- Mice, Transgenic
- Signal Transduction
- Syndecan-2 -- physiology
- Tissue Array Analysis
- Transforming Growth Factor beta1 -- drug effects
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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