Combustion-derived flame generated ultrafine soot generates reactive oxygen species and activates Nrf2 antioxidants differently in neonatal and adult rat lungs. [electronic resource]
Producer: 20130930Description: 34 p. digitalISSN:- 1743-8977
- Age Factors
- Animals
- Animals, Newborn
- Antioxidants -- metabolism
- Catalase -- genetics
- Dose-Response Relationship, Drug
- Gene Expression Regulation, Enzymologic -- drug effects
- Genes, Reporter
- Heme Oxygenase (Decyclizing) -- genetics
- Humans
- Inhalation Exposure
- Lung -- drug effects
- Male
- NF-E2-Related Factor 2 -- genetics
- Oxidative Stress -- drug effects
- Particle Size
- Peroxiredoxin VI -- genetics
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Soot -- toxicity
- Superoxide Dismutase -- genetics
- Superoxide Dismutase-1
- Time Factors
- Transfection
- U937 Cells
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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