Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1. [electronic resource]
Producer: 20140218Description: e1003496 p. digitalISSN:- 1553-7374
- Animals
- Cercopithecinae
- Databases, Protein
- Evolution, Molecular
- HEK293 Cells
- HIV-2 -- genetics
- Host-Pathogen Interactions
- Humans
- Models, Biological
- Monomeric GTP-Binding Proteins -- chemistry
- Mutant Proteins -- chemistry
- Peptide Fragments -- chemistry
- Phylogeny
- Proteasome Endopeptidase Complex
- Protein Interaction Domains and Motifs
- Protein Stability
- Recombinant Fusion Proteins -- chemistry
- SAM Domain and HD Domain-Containing Protein 1
- Simian Immunodeficiency Virus -- genetics
- Ubiquitination
- Viral Regulatory and Accessory Proteins -- chemistry
- vpr Gene Products, Human Immunodeficiency Virus -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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