Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.

Fregoso, Oliver I

Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1. [electronic resource] - PLoS pathogens 2013 - e1003496 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1553-7374

10.1371/journal.ppat.1003496 doi


Animals
Cercopithecinae
Databases, Protein
Evolution, Molecular
HEK293 Cells
HIV-2--genetics
Host-Pathogen Interactions
Humans
Models, Biological
Monomeric GTP-Binding Proteins--chemistry
Mutant Proteins--chemistry
Peptide Fragments--chemistry
Phylogeny
Proteasome Endopeptidase Complex
Protein Interaction Domains and Motifs
Protein Stability
Recombinant Fusion Proteins--chemistry
SAM Domain and HD Domain-Containing Protein 1
Simian Immunodeficiency Virus--genetics
Ubiquitination
Viral Regulatory and Accessory Proteins--chemistry
vpr Gene Products, Human Immunodeficiency Virus--chemistry