Inhibition of Wnt/β-catenin signaling downregulates P-glycoprotein and reverses multi-drug resistance of cholangiocarcinoma. [electronic resource]
Producer: 20131126Description: 1303-8 p. digitalISSN:- 1349-7006
- ATP Binding Cassette Transporter, Subfamily B -- biosynthesis
- Alligators and Crocodiles
- Animals
- Antineoplastic Agents -- pharmacology
- Bile -- chemistry
- Bile Duct Neoplasms -- genetics
- Bile Ducts, Intrahepatic -- metabolism
- Cell Cycle
- Cell Line, Tumor -- drug effects
- Cell Size
- Cholangiocarcinoma -- genetics
- Down-Regulation -- drug effects
- Drug Resistance, Multiple -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Neoplasm Proteins -- antagonists & inhibitors
- RNA Interference
- RNA, Small Interfering -- pharmacology
- Real-Time Polymerase Chain Reaction
- Tissue Extracts -- pharmacology
- Wnt Signaling Pathway -- drug effects
- Wnt3A Protein -- pharmacology
- beta Catenin -- antagonists & inhibitors
- ATP-Binding Cassette Sub-Family B Member 4
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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