Dual evaluation of some novel 2-amino-substituted coumarinylthiazoles as anti-inflammatory-antimicrobial agents and their docking studies with COX-1/COX-2 active sites. [electronic resource]
Producer: 20150403Description: 476-84 p. digitalISSN:- 1475-6374
- Animals
- Anti-Bacterial Agents -- chemical synthesis
- Anti-Inflammatory Agents, Non-Steroidal -- chemical synthesis
- Antifungal Agents -- chemical synthesis
- Candida albicans -- drug effects
- Carrageenan
- Catalytic Domain -- drug effects
- Coumarins -- chemical synthesis
- Cyclooxygenase 1 -- chemistry
- Cyclooxygenase 2 -- chemistry
- Cyclooxygenase Inhibitors -- chemical synthesis
- Dose-Response Relationship, Drug
- Edema -- chemically induced
- Gram-Negative Bacteria -- drug effects
- Gram-Positive Bacteria -- drug effects
- Humans
- Male
- Molecular Docking Simulation
- Molecular Structure
- Rats
- Rats, Wistar
- Saccharomyces cerevisiae -- drug effects
- Structure-Activity Relationship
- Thiazoles -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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