Dual evaluation of some novel 2-amino-substituted coumarinylthiazoles as anti-inflammatory-antimicrobial agents and their docking studies with COX-1/COX-2 active sites.

Chandak, Navneet

Dual evaluation of some novel 2-amino-substituted coumarinylthiazoles as anti-inflammatory-antimicrobial agents and their docking studies with COX-1/COX-2 active sites. [electronic resource] - Journal of enzyme inhibition and medicinal chemistry Aug 2014 - 476-84 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1475-6374

10.3109/14756366.2013.805755 doi


Animals
Anti-Bacterial Agents--chemical synthesis
Anti-Inflammatory Agents, Non-Steroidal--chemical synthesis
Antifungal Agents--chemical synthesis
Candida albicans--drug effects
Carrageenan
Catalytic Domain--drug effects
Coumarins--chemical synthesis
Cyclooxygenase 1--chemistry
Cyclooxygenase 2--chemistry
Cyclooxygenase Inhibitors--chemical synthesis
Dose-Response Relationship, Drug
Edema--chemically induced
Gram-Negative Bacteria--drug effects
Gram-Positive Bacteria--drug effects
Humans
Male
Molecular Docking Simulation
Molecular Structure
Rats
Rats, Wistar
Saccharomyces cerevisiae--drug effects
Structure-Activity Relationship
Thiazoles--chemical synthesis