13-methyltetradecanoic acid exhibits anti-tumor activity on T-cell lymphomas in vitro and in vivo by down-regulating p-AKT and activating caspase-3. [electronic resource]
Producer: 20140122Description: e65308 p. digitalISSN:- 1932-6203
- Animals
- Apoptosis -- drug effects
- Blotting, Western
- Caspase 3 -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Down-Regulation -- drug effects
- Enzyme Activation -- drug effects
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Lymphoma, T-Cell -- drug therapy
- Mice
- Mice, Nude
- Myristic Acids -- administration & dosage
- NF-kappa B -- metabolism
- Neoplasm Proteins -- metabolism
- Phosphorylation -- drug effects
- Poly(ADP-ribose) Polymerases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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