Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis. [electronic resource]
Producer: 20140225Description: e661 p. digitalISSN:- 2041-4889
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cyclin B -- genetics
- Cyclin E -- genetics
- Dexamethasone -- pharmacology
- Doxorubicin -- pharmacology
- Drug Resistance, Neoplasm
- Drug Synergism
- G1 Phase Cell Cycle Checkpoints
- G2 Phase Cell Cycle Checkpoints
- Gene Knockdown Techniques
- HCT116 Cells
- Humans
- Methotrexate -- pharmacology
- Mice
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy
- RNA, Small Interfering -- genetics
- TNF-Related Apoptosis-Inducing Ligand -- pharmacology
- Tumor Suppressor Protein p53 -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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