Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis.
Ehrhardt, H
Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis. [electronic resource] - Cell death & disease Jun 2013 - e661 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2041-4889
10.1038/cddis.2013.179 doi
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cyclin B--genetics
Cyclin E--genetics
Dexamethasone--pharmacology
Doxorubicin--pharmacology
Drug Resistance, Neoplasm
Drug Synergism
G1 Phase Cell Cycle Checkpoints
G2 Phase Cell Cycle Checkpoints
Gene Knockdown Techniques
HCT116 Cells
Humans
Methotrexate--pharmacology
Mice
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
RNA, Small Interfering--genetics
TNF-Related Apoptosis-Inducing Ligand--pharmacology
Tumor Suppressor Protein p53--metabolism
Xenograft Model Antitumor Assays
Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis. [electronic resource] - Cell death & disease Jun 2013 - e661 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2041-4889
10.1038/cddis.2013.179 doi
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cyclin B--genetics
Cyclin E--genetics
Dexamethasone--pharmacology
Doxorubicin--pharmacology
Drug Resistance, Neoplasm
Drug Synergism
G1 Phase Cell Cycle Checkpoints
G2 Phase Cell Cycle Checkpoints
Gene Knockdown Techniques
HCT116 Cells
Humans
Methotrexate--pharmacology
Mice
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
RNA, Small Interfering--genetics
TNF-Related Apoptosis-Inducing Ligand--pharmacology
Tumor Suppressor Protein p53--metabolism
Xenograft Model Antitumor Assays