Androgens up-regulate transcription of the Notch inhibitor Numb in C2C12 myoblasts via Wnt/β-catenin signaling to T cell factor elements in the Numb promoter. [electronic resource]
Producer: 20130906Description: 17990-8 p. digitalISSN:- 1083-351X
- Androgens -- pharmacology
- Animals
- Binding Sites -- genetics
- Blotting, Western
- Cell Line
- Gene Expression -- drug effects
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Membrane Proteins -- genetics
- Mice
- Microscopy, Confocal
- Mutation
- Myoblasts -- cytology
- Nandrolone -- pharmacology
- Nerve Tissue Proteins -- genetics
- Promoter Regions, Genetic -- genetics
- Protein Binding
- RNA Interference
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- TCF Transcription Factors -- metabolism
- Transcription, Genetic -- drug effects
- Up-Regulation -- drug effects
- Wnt Proteins -- genetics
- Wnt3A Protein -- genetics
- beta Catenin -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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