Androgens up-regulate transcription of the Notch inhibitor Numb in C2C12 myoblasts via Wnt/β-catenin signaling to T cell factor elements in the Numb promoter.

Liu, Xin-Hua

Androgens up-regulate transcription of the Notch inhibitor Numb in C2C12 myoblasts via Wnt/β-catenin signaling to T cell factor elements in the Numb promoter. [electronic resource] - The Journal of biological chemistry Jun 2013 - 17990-8 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

1083-351X

10.1074/jbc.M113.478487 doi


Androgens--pharmacology
Animals
Binding Sites--genetics
Blotting, Western
Cell Line
Gene Expression--drug effects
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Membrane Proteins--genetics
Mice
Microscopy, Confocal
Mutation
Myoblasts--cytology
Nandrolone--pharmacology
Nerve Tissue Proteins--genetics
Promoter Regions, Genetic--genetics
Protein Binding
RNA Interference
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects
TCF Transcription Factors--metabolism
Transcription, Genetic--drug effects
Up-Regulation--drug effects
Wnt Proteins--genetics
Wnt3A Protein--genetics
beta Catenin--genetics