Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors. [electronic resource]
Producer: 20131210Description: 7223-34 p. digitalISSN:- 1520-5126
- Animals
- Antineoplastic Agents -- chemical synthesis
- Bone Neoplasms -- drug therapy
- Bone and Bones -- drug effects
- Cell Line, Tumor
- Cyclization
- Humans
- Indoles -- chemical synthesis
- Mice, SCID
- Models, Molecular
- Osteosarcoma -- drug therapy
- Oxindoles
- Proto-Oncogene Proteins c-mdm2 -- antagonists & inhibitors
- Spiro Compounds -- chemical synthesis
- Stereoisomerism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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