Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors. (Record no. 22722042)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01798 a2200529 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516150150.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201312s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-5126 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/ja3125417 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Zhao, Yujun |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20131210 |
| 245 00 - TITLE STATEMENT | |
| Title | Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of the American Chemical Society |
| Date of publication, distribution, etc. | May 2013 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 7223-34 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Agents |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bone Neoplasms |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bone and Bones |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cyclization |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Indoles |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, SCID |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Osteosarcoma |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Oxindoles |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proto-Oncogene Proteins c-mdm2 |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Spiro Compounds |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Stereoisomerism |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, Liu |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sun, Wei |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lu, Jianfeng |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McEachern, Donna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, Xiaoqin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yu, Shanghai |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bernard, Denzil |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ochsenbein, Philippe |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ferey, Vincent |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Carry, Jean-Christophe |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Deschamps, Jeffrey R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sun, Duxin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wang, Shaomeng |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of the American Chemical Society |
| Related parts | vol. 135 |
| -- | no. 19 |
| -- | p. 7223-34 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/ja3125417">https://doi.org/10.1021/ja3125417</a> |
| Public note | Available from publisher's website |
No items available.