High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine xenograft model in vivo. [electronic resource]
Producer: 20130917Description: e58757 p. digitalISSN:- 1932-6203
- Animals
- Cell Lineage
- Dependovirus -- classification
- Erythroid Cells -- cytology
- Female
- Gene Expression
- Genetic Vectors -- genetics
- HEK293 Cells
- Hematopoietic Stem Cells -- cytology
- Humans
- K562 Cells
- Mice
- Mutation
- Promoter Regions, Genetic -- genetics
- Serotyping
- Transcription, Genetic
- Transduction, Genetic -- methods
- Transgenes -- genetics
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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