High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine xenograft model in vivo.
Song, Liujiang
High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine xenograft model in vivo. [electronic resource] - PloS one 2013 - e58757 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0058757 doi
Animals
Cell Lineage
Dependovirus--classification
Erythroid Cells--cytology
Female
Gene Expression
Genetic Vectors--genetics
HEK293 Cells
Hematopoietic Stem Cells--cytology
Humans
K562 Cells
Mice
Mutation
Promoter Regions, Genetic--genetics
Serotyping
Transcription, Genetic
Transduction, Genetic--methods
Transgenes--genetics
Transplantation, Heterologous
High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine xenograft model in vivo. [electronic resource] - PloS one 2013 - e58757 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0058757 doi
Animals
Cell Lineage
Dependovirus--classification
Erythroid Cells--cytology
Female
Gene Expression
Genetic Vectors--genetics
HEK293 Cells
Hematopoietic Stem Cells--cytology
Humans
K562 Cells
Mice
Mutation
Promoter Regions, Genetic--genetics
Serotyping
Transcription, Genetic
Transduction, Genetic--methods
Transgenes--genetics
Transplantation, Heterologous