GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models. [electronic resource]
Producer: 20130611Description: 2911-35 p. digitalISSN:- 1520-4804
- Animals
- Antineoplastic Agents -- pharmacology
- Benzodiazepines -- chemistry
- Cell Line, Tumor
- Disease Models, Animal
- Drug Screening Assays, Antitumor
- Fluorescence Resonance Energy Transfer
- GC Rich Sequence
- Humans
- In Vitro Techniques
- Magnetic Resonance Spectroscopy
- Mice
- Models, Molecular
- Molecular Structure
- NF-kappa B -- antagonists & inhibitors
- Spectrometry, Mass, Electrospray Ionization
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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