GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models. (Record no. 22600967)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01852 a2200529 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516141831.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201306s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm301882a |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Rahman, Khondaker M |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20130611 |
| 245 00 - TITLE STATEMENT | |
| Title | GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Apr 2013 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 2911-35 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Agents |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Benzodiazepines |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Disease Models, Animal |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Screening Assays, Antitumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Fluorescence Resonance Energy Transfer |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | GC Rich Sequence |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | In Vitro Techniques |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Magnetic Resonance Spectroscopy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Structure |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | NF-kappa B |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Spectrometry, Mass, Electrospray Ionization |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jackson, Paul J M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | James, Colin H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Basu, B Piku |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hartley, John A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | de la Fuente, Maria |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schatzlein, Andreas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Robson, Mathew |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pedley, R Barbara |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pepper, Chris |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fox, Keith R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Howard, Philip W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thurston, David E |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 56 |
| -- | no. 7 |
| -- | p. 2911-35 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm301882a">https://doi.org/10.1021/jm301882a</a> |
| Public note | Available from publisher's website |
No items available.