Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging. [electronic resource]
Producer: 20130814Description: 435-45 p. digitalISSN:- 1474-9726
- Animals
- Cell Cycle -- genetics
- Cells, Cultured
- Cellular Senescence -- genetics
- Hepatocytes -- metabolism
- Longevity
- Mice
- Mice, Knockout
- Oxidative Stress -- physiology
- Peptide Fragments -- metabolism
- Protein Isoforms -- genetics
- Shc Signaling Adaptor Proteins -- genetics
- Src Homology 2 Domain-Containing, Transforming Protein 1
- Thymus Gland -- metabolism
- Transcription Factors
- Transcription, Genetic
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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