Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging.

Gambino, Valentina

Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging. [electronic resource] - Aging cell Jun 2013 - 435-45 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1474-9726

10.1111/acel.12060 doi


Animals
Cell Cycle--genetics
Cells, Cultured
Cellular Senescence--genetics
Hepatocytes--metabolism
Longevity
Mice
Mice, Knockout
Oxidative Stress--physiology
Peptide Fragments--metabolism
Protein Isoforms--genetics
Shc Signaling Adaptor Proteins--genetics
Src Homology 2 Domain-Containing, Transforming Protein 1
Thymus Gland--metabolism
Transcription Factors
Transcription, Genetic
Tumor Suppressor Protein p53--genetics