MicroRNA-195 protects against dementia induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats. [electronic resource]
Producer: 20130422Description: 3989-4001 p. digitalISSN:- 1529-2401
- Aged
- Aged, 80 and over
- Amyloid Precursor Protein Secretases -- genetics
- Amyloid beta-Peptides -- blood
- Amyloid beta-Protein Precursor -- genetics
- Analysis of Variance
- Animals
- Animals, Newborn
- Aspartic Acid Endopeptidases -- genetics
- Carotid Artery Diseases -- complications
- Cells, Cultured
- Cerebral Cortex -- cytology
- Dementia -- etiology
- Disease Models, Animal
- Enzyme-Linked Immunosorbent Assay
- Female
- Gene Expression Regulation -- drug effects
- Hippocampus -- cytology
- Humans
- Immunoprecipitation
- Lipopolysaccharides -- pharmacology
- Male
- Maze Learning -- drug effects
- MicroRNAs -- biosynthesis
- Neurons -- drug effects
- Neuroprotective Agents -- metabolism
- Oligonucleotides, Antisense -- pharmacology
- Peptide Fragments -- metabolism
- Protein Serine-Threonine Kinases -- genetics
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Transfection
- NF-kappaB-Inducing Kinase
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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