Induction of p16(INK4a) is the major barrier to proliferation when Epstein-Barr virus (EBV) transforms primary B cells into lymphoblastoid cell lines. [electronic resource]
Producer: 20140820Description: e1003187 p. digitalISSN:- 1553-7374
- Antigens, Viral -- genetics
- B-Lymphocytes -- virology
- Cell Line
- Cell Proliferation
- Cell Survival
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- Epigenetic Repression -- genetics
- Epstein-Barr Virus Infections -- immunology
- Epstein-Barr Virus Nuclear Antigens -- genetics
- Genetic Loci
- Herpesvirus 4, Human -- immunology
- Humans
- Lymphocyte Activation
- Oligonucleotide Array Sequence Analysis
- Phosphorylation
- Primary Cell Culture
- Virus Latency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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