Human lipopolysaccharide-binding protein (LBP) and CD14 independently deliver triacylated lipoproteins to Toll-like receptor 1 (TLR1) and TLR2 and enhance formation of the ternary signaling complex. [electronic resource]
Producer: 20130531Description: 9729-9741 p. digitalISSN:- 1083-351X
- Acute-Phase Proteins
- Bacteremia -- microbiology
- Bacterial Proteins -- metabolism
- Binding, Competitive
- Carrier Proteins
- Enzyme-Linked Immunosorbent Assay -- methods
- HEK293 Cells
- Humans
- Immunity, Innate
- Inflammation
- Lipopeptides -- chemistry
- Lipopolysaccharide Receptors -- biosynthesis
- Membrane Glycoproteins
- Protein Binding
- Recombinant Proteins -- chemistry
- Sepsis -- microbiology
- Signal Transduction
- Toll-Like Receptor 1 -- metabolism
- Toll-Like Receptor 2 -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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