Human lipopolysaccharide-binding protein (LBP) and CD14 independently deliver triacylated lipoproteins to Toll-like receptor 1 (TLR1) and TLR2 and enhance formation of the ternary signaling complex.
Ranoa, Diana Rose E
Human lipopolysaccharide-binding protein (LBP) and CD14 independently deliver triacylated lipoproteins to Toll-like receptor 1 (TLR1) and TLR2 and enhance formation of the ternary signaling complex. [electronic resource] - The Journal of biological chemistry Apr 2013 - 9729-9741 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.M113.453266 doi
Acute-Phase Proteins
Bacteremia--microbiology
Bacterial Proteins--metabolism
Binding, Competitive
Carrier Proteins
Enzyme-Linked Immunosorbent Assay--methods
HEK293 Cells
Humans
Immunity, Innate
Inflammation
Lipopeptides--chemistry
Lipopolysaccharide Receptors--biosynthesis
Membrane Glycoproteins
Protein Binding
Recombinant Proteins--chemistry
Sepsis--microbiology
Signal Transduction
Toll-Like Receptor 1--metabolism
Toll-Like Receptor 2--metabolism
Human lipopolysaccharide-binding protein (LBP) and CD14 independently deliver triacylated lipoproteins to Toll-like receptor 1 (TLR1) and TLR2 and enhance formation of the ternary signaling complex. [electronic resource] - The Journal of biological chemistry Apr 2013 - 9729-9741 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.M113.453266 doi
Acute-Phase Proteins
Bacteremia--microbiology
Bacterial Proteins--metabolism
Binding, Competitive
Carrier Proteins
Enzyme-Linked Immunosorbent Assay--methods
HEK293 Cells
Humans
Immunity, Innate
Inflammation
Lipopeptides--chemistry
Lipopolysaccharide Receptors--biosynthesis
Membrane Glycoproteins
Protein Binding
Recombinant Proteins--chemistry
Sepsis--microbiology
Signal Transduction
Toll-Like Receptor 1--metabolism
Toll-Like Receptor 2--metabolism