The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury. [electronic resource]
Producer: 20140422Description: 90-103 p. digitalISSN:- 1523-1755
- 5'-Nucleotidase -- antagonists & inhibitors
- Acute Kidney Injury -- enzymology
- Adenosine -- metabolism
- Anesthetics, Inhalation -- pharmacology
- Animals
- Antibodies, Neutralizing -- pharmacology
- Apoptosis -- drug effects
- Cell Line
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Enzyme Induction
- Enzyme Inhibitors -- pharmacology
- GPI-Linked Proteins -- antagonists & inhibitors
- Humans
- Isoflurane -- pharmacology
- Kidney Tubules, Proximal -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Necrosis
- Neutrophil Infiltration -- drug effects
- Purinergic P1 Receptor Antagonists -- pharmacology
- RNA, Messenger -- metabolism
- Reperfusion Injury -- enzymology
- Time Factors
- Transforming Growth Factor beta1 -- antagonists & inhibitors
- Volatilization
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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