The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury.

Kim, Mihwa

The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury. [electronic resource] - Kidney international Jul 2013 - 90-103 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1523-1755

10.1038/ki.2013.43 doi


5'-Nucleotidase--antagonists & inhibitors
Acute Kidney Injury--enzymology
Adenosine--metabolism
Anesthetics, Inhalation--pharmacology
Animals
Antibodies, Neutralizing--pharmacology
Apoptosis--drug effects
Cell Line
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Induction
Enzyme Inhibitors--pharmacology
GPI-Linked Proteins--antagonists & inhibitors
Humans
Isoflurane--pharmacology
Kidney Tubules, Proximal--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Necrosis
Neutrophil Infiltration--drug effects
Purinergic P1 Receptor Antagonists--pharmacology
RNA, Messenger--metabolism
Reperfusion Injury--enzymology
Time Factors
Transforming Growth Factor beta1--antagonists & inhibitors
Volatilization