Inhibition of overactive transforming growth factor-β signaling by prostacyclin analogs in pulmonary arterial hypertension. [electronic resource]
Producer: 20130805Description: 733-41 p. digitalISSN:- 1535-4989
- Animals
- Bone Morphogenetic Protein Receptors, Type II -- genetics
- Cell Proliferation -- drug effects
- Codon, Nonsense
- Epoprostenol -- analogs & derivatives
- Familial Primary Pulmonary Hypertension
- HEK293 Cells
- Humans
- Hypertension, Pulmonary -- metabolism
- Lung -- drug effects
- MAP Kinase Signaling System
- Male
- Mice
- Monocrotaline -- pharmacology
- Myocytes, Smooth Muscle -- drug effects
- Phosphorylation
- Protein Serine-Threonine Kinases -- genetics
- Rats
- Rats, Sprague-Dawley
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Transforming Growth Factor beta -- genetics
- Smad3 Protein -- genetics
- Transforming Growth Factor beta1 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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