Morphine induces bacterial translocation in mice by compromising intestinal barrier function in a TLR-dependent manner. [electronic resource]
Producer: 20130724Description: e54040 p. digitalISSN:- 1932-6203
- Analgesics, Opioid -- pharmacology
- Animals
- Azepines -- pharmacology
- Bacterial Translocation -- drug effects
- Blotting, Western
- Cell Line
- Colon -- drug effects
- Epithelium -- drug effects
- Ileum -- drug effects
- Intestinal Mucosa -- metabolism
- Intestines -- drug effects
- Liver -- drug effects
- Lymph Nodes -- drug effects
- Mesentery
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Microscopy, Fluorescence
- Morphine -- pharmacology
- Myosin-Light-Chain Kinase -- antagonists & inhibitors
- Naphthalenes -- pharmacology
- Receptors, Opioid, mu -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Tight Junctions -- drug effects
- Toll-Like Receptor 2 -- genetics
- Toll-Like Receptor 4 -- genetics
- Zonula Occludens-1 Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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