Preparation and evaluation of a new releasable PEGylated tumor necrosis factor-α (TNF-α) conjugate for therapeutic application. [electronic resource]
Producer: 20130701Description: 51-8 p. digitalISSN:- 1869-1889
- Animals
- Antineoplastic Agents -- chemistry
- Cathepsin B -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Survival -- drug effects
- Dipeptides -- chemistry
- Dose-Response Relationship, Drug
- Drug Compounding
- Drug Evaluation, Preclinical
- Glycopeptides -- pharmacology
- Humans
- Hydrogen-Ion Concentration
- Leucine -- analogs & derivatives
- Lysosomes -- enzymology
- Male
- Mice
- Mice, Inbred C57BL
- Neoplasms, Experimental -- drug therapy
- Pepstatins -- pharmacology
- Polyethylene Glycols -- chemistry
- Protease Inhibitors -- pharmacology
- Rats
- Time Factors
- Tumor Burden -- drug effects
- Tumor Necrosis Factor-alpha -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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