TLR7 triggering with polyuridylic acid promotes cross-presentation in CD8α+ conventional dendritic cells by enhancing antigen preservation and MHC class I antigen permanence on the dendritic cell surface. [electronic resource]
Producer: 20130326Description: 948-60 p. digitalISSN:- 1550-6606
- Adjuvants, Immunologic -- pharmacology
- Animals
- Antigen Presentation -- drug effects
- Antigens -- immunology
- CD8-Positive T-Lymphocytes -- drug effects
- Cell Compartmentation
- Cells, Cultured -- immunology
- Cytotoxicity, Immunologic
- Dendritic Cells -- drug effects
- Endosomes -- immunology
- Female
- H-2 Antigens -- immunology
- Membrane Glycoproteins -- drug effects
- Membrane Proteins -- physiology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Ovalbumin -- immunology
- Peptide Fragments -- immunology
- Phagosomes -- immunology
- Poly U -- pharmacology
- Proteasome Endopeptidase Complex -- metabolism
- Protein Transport
- Receptors, Antigen, T-Cell, alpha-beta -- immunology
- SEC Translocation Channels
- Spleen -- immunology
- Toll-Like Receptor 7 -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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