TLR7 triggering with polyuridylic acid promotes cross-presentation in CD8α+ conventional dendritic cells by enhancing antigen preservation and MHC class I antigen permanence on the dendritic cell surface.

Crespo, María I

TLR7 triggering with polyuridylic acid promotes cross-presentation in CD8α+ conventional dendritic cells by enhancing antigen preservation and MHC class I antigen permanence on the dendritic cell surface. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Feb 2013 - 948-60 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1550-6606

10.4049/jimmunol.1102725 doi


Adjuvants, Immunologic--pharmacology
Animals
Antigen Presentation--drug effects
Antigens--immunology
CD8-Positive T-Lymphocytes--drug effects
Cell Compartmentation
Cells, Cultured--immunology
Cytotoxicity, Immunologic
Dendritic Cells--drug effects
Endosomes--immunology
Female
H-2 Antigens--immunology
Membrane Glycoproteins--drug effects
Membrane Proteins--physiology
Mice
Mice, Inbred C57BL
Mice, Knockout
Ovalbumin--immunology
Peptide Fragments--immunology
Phagosomes--immunology
Poly U--pharmacology
Proteasome Endopeptidase Complex--metabolism
Protein Transport
Receptors, Antigen, T-Cell, alpha-beta--immunology
SEC Translocation Channels
Spleen--immunology
Toll-Like Receptor 7--drug effects