Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction. [electronic resource]
Producer: 20130417Description: 1734-49 p. digitalISSN:- 1362-4962
- Antigens, Nuclear -- genetics
- Cell Line, Tumor
- Cell Proliferation
- Chromatids
- Chromosome Aberrations
- DNA Damage
- DNA End-Joining Repair
- DNA Helicases -- genetics
- DNA Ligase ATP
- DNA Ligases -- genetics
- DNA-Binding Proteins -- genetics
- Gene Targeting
- Genomic Instability
- Humans
- Ku Autoantigen
- Mutation
- Nuclear Proteins -- genetics
- Recombination, Genetic
- Recombinational DNA Repair
- Telomere -- physiology
- Telomere Homeostasis
- Telomeric Repeat Binding Protein 2 -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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