Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction.
Oh, Sehyun
Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction. [electronic resource] - Nucleic acids research Feb 2013 - 1734-49 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1362-4962
10.1093/nar/gks1326 doi
Antigens, Nuclear--genetics
Cell Line, Tumor
Cell Proliferation
Chromatids
Chromosome Aberrations
DNA Damage
DNA End-Joining Repair
DNA Helicases--genetics
DNA Ligase ATP
DNA Ligases--genetics
DNA-Binding Proteins--genetics
Gene Targeting
Genomic Instability
Humans
Ku Autoantigen
Mutation
Nuclear Proteins--genetics
Recombination, Genetic
Recombinational DNA Repair
Telomere--physiology
Telomere Homeostasis
Telomeric Repeat Binding Protein 2--metabolism
Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction. [electronic resource] - Nucleic acids research Feb 2013 - 1734-49 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1362-4962
10.1093/nar/gks1326 doi
Antigens, Nuclear--genetics
Cell Line, Tumor
Cell Proliferation
Chromatids
Chromosome Aberrations
DNA Damage
DNA End-Joining Repair
DNA Helicases--genetics
DNA Ligase ATP
DNA Ligases--genetics
DNA-Binding Proteins--genetics
Gene Targeting
Genomic Instability
Humans
Ku Autoantigen
Mutation
Nuclear Proteins--genetics
Recombination, Genetic
Recombinational DNA Repair
Telomere--physiology
Telomere Homeostasis
Telomeric Repeat Binding Protein 2--metabolism