Sarcophine-diol inhibits expression of COX-2, inhibits activity of cPLA2, enhances degradation of PLA2 and PLC(γ)1 and inhibits cell membrane permeability in mouse melanoma B16F10 cells. [electronic resource]
Producer: 20130503Description: 2166-2180 p. digitalISSN:- 1660-3397
- Animals
- Anthozoa -- chemistry
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Cell Membrane Permeability -- drug effects
- Cell Proliferation
- Cyclooxygenase 2 -- genetics
- Cyclooxygenase 2 Inhibitors -- pharmacology
- Diterpenes -- chemistry
- Gene Expression Regulation, Enzymologic
- Melanoma -- metabolism
- Mice
- Molecular Structure
- Phospholipase C gamma -- genetics
- Phospholipases A2, Cytosolic -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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