Insights into the molecular mechanism for type 2 diabetes susceptibility at the KCNQ1 locus from temporal changes in imprinting status in human islets. [electronic resource]
Producer: 20130417Description: 987-92 p. digitalISSN:- 1939-327X
- Adult
- Alleles
- Chromosomes, Human, Pair 11 -- genetics
- Cohort Studies
- Cyclin-Dependent Kinase Inhibitor p57 -- genetics
- DNA Methylation
- Diabetes Mellitus, Type 2 -- genetics
- Fetal Development
- Gene Expression Regulation, Developmental
- Genetic Association Studies
- Genetic Loci
- Genetic Predisposition to Disease
- Humans
- Introns
- Islets of Langerhans -- growth & development
- KCNQ1 Potassium Channel -- genetics
- Pancreas -- embryology
- Polymorphism, Single Nucleotide
- Potassium Channels, Voltage-Gated -- genetics
- United Kingdom
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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