Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells. [electronic resource]
Producer: 20130814Description: 1215-29 p. digitalISSN:- 1476-5381
- Action Potentials -- drug effects
- Animals
- Cells, Cultured
- Ether-A-Go-Go Potassium Channels -- antagonists & inhibitors
- HEK293 Cells
- Humans
- Hypnotics and Sedatives -- pharmacology
- Induced Pluripotent Stem Cells -- cytology
- Long QT Syndrome -- chemically induced
- Myocytes, Cardiac -- drug effects
- Oocytes -- drug effects
- Potassium Channel Blockers -- pharmacology
- Pyridines -- pharmacology
- Recombinant Proteins
- Xenopus laevis
- Zolpidem
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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