Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator. [electronic resource]
Producer: 20130710Description: 1657-72 p. digitalISSN:- 1554-8635
- Adaptor Proteins, Signal Transducing -- metabolism
- Adolescent
- Animals
- Antioxidants -- pharmacology
- Apoptosis Regulatory Proteins -- metabolism
- Autophagy -- drug effects
- Beclin-1
- Cell Membrane -- drug effects
- Child
- Cystamine -- pharmacology
- Cystic Fibrosis -- drug therapy
- Cystic Fibrosis Transmembrane Conductance Regulator -- metabolism
- Epithelial Cells -- drug effects
- Epithelium -- drug effects
- Female
- Genistein -- pharmacology
- Heat-Shock Proteins -- metabolism
- Humans
- Inflammation -- pathology
- Lipopolysaccharides -- pharmacology
- Lung -- drug effects
- Male
- Membrane Proteins -- metabolism
- Mice
- Molecular Targeted Therapy
- Nasal Mucosa -- drug effects
- Nasal Polyps -- pathology
- Organometallic Compounds -- pharmacology
- Protein Glutamine gamma Glutamyltransferase 2
- Salicylates -- pharmacology
- Sequestosome-1 Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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