Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator.
Luciani, Alessandro
Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator. [electronic resource] - Autophagy Nov 2012 - 1657-72 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1554-8635
10.4161/auto.21483 doi
Adaptor Proteins, Signal Transducing--metabolism
Adolescent
Animals
Antioxidants--pharmacology
Apoptosis Regulatory Proteins--metabolism
Autophagy--drug effects
Beclin-1
Cell Membrane--drug effects
Child
Cystamine--pharmacology
Cystic Fibrosis--drug therapy
Cystic Fibrosis Transmembrane Conductance Regulator--metabolism
Epithelial Cells--drug effects
Epithelium--drug effects
Female
Genistein--pharmacology
Heat-Shock Proteins--metabolism
Humans
Inflammation--pathology
Lipopolysaccharides--pharmacology
Lung--drug effects
Male
Membrane Proteins--metabolism
Mice
Molecular Targeted Therapy
Nasal Mucosa--drug effects
Nasal Polyps--pathology
Organometallic Compounds--pharmacology
Protein Glutamine gamma Glutamyltransferase 2
Salicylates--pharmacology
Sequestosome-1 Protein
Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator. [electronic resource] - Autophagy Nov 2012 - 1657-72 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1554-8635
10.4161/auto.21483 doi
Adaptor Proteins, Signal Transducing--metabolism
Adolescent
Animals
Antioxidants--pharmacology
Apoptosis Regulatory Proteins--metabolism
Autophagy--drug effects
Beclin-1
Cell Membrane--drug effects
Child
Cystamine--pharmacology
Cystic Fibrosis--drug therapy
Cystic Fibrosis Transmembrane Conductance Regulator--metabolism
Epithelial Cells--drug effects
Epithelium--drug effects
Female
Genistein--pharmacology
Heat-Shock Proteins--metabolism
Humans
Inflammation--pathology
Lipopolysaccharides--pharmacology
Lung--drug effects
Male
Membrane Proteins--metabolism
Mice
Molecular Targeted Therapy
Nasal Mucosa--drug effects
Nasal Polyps--pathology
Organometallic Compounds--pharmacology
Protein Glutamine gamma Glutamyltransferase 2
Salicylates--pharmacology
Sequestosome-1 Protein