Functional differences exist between TNFα promoters encoding the common -237G SNP and the rarer HLA-B*5701-linked A variant. [electronic resource]
Producer: 20130319Description: e40100 p. digitalISSN:- 1932-6203
- Animals
- B-Lymphocytes -- drug effects
- Base Sequence
- Cell Line
- DNA Methylation -- drug effects
- Epigenesis, Genetic -- drug effects
- Genes, Reporter
- HIV Infections -- genetics
- HLA-B Antigens -- genetics
- Haplotypes -- genetics
- Homozygote
- Humans
- Lipopolysaccharides -- pharmacology
- Luciferases -- metabolism
- Lymphocyte Activation -- drug effects
- Mice
- Molecular Sequence Data
- Monocytes -- cytology
- Polymorphism, Single Nucleotide -- genetics
- Promoter Regions, Genetic -- genetics
- Protein Binding -- drug effects
- RNA, Messenger -- genetics
- Software
- Solubility
- Tetradecanoylphorbol Acetate -- pharmacology
- Transcription Factors -- metabolism
- Tumor Necrosis Factor-alpha -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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