Conjugated linoleic acids attenuate FSH- and IGF1-stimulated cell proliferation; IGF1, GATA4, and aromatase expression; and estradiol-17β production in buffalo granulosa cells involving PPARγ, PTEN, and PI3K/Akt. [electronic resource]
Producer: 20130103Description: 373-83 p. digitalISSN:- 1741-7899
- Animals
- Aromatase -- genetics
- Buffaloes -- metabolism
- Cell Proliferation -- drug effects
- Cells, Cultured
- Estradiol -- biosynthesis
- Female
- Follicle Stimulating Hormone -- pharmacology
- GATA4 Transcription Factor -- genetics
- Gene Expression -- drug effects
- Granulosa Cells -- cytology
- Insulin-Like Growth Factor I -- genetics
- Linoleic Acids, Conjugated -- pharmacology
- PPAR gamma -- physiology
- PTEN Phosphohydrolase -- antagonists & inhibitors
- Phosphatidylinositol 3-Kinases -- physiology
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt -- physiology
- RNA, Messenger -- analysis
- Signal Transduction -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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