Conjugated linoleic acids attenuate FSH- and IGF1-stimulated cell proliferation; IGF1, GATA4, and aromatase expression; and estradiol-17β production in buffalo granulosa cells involving PPARγ, PTEN, and PI3K/Akt.
Sharma, Isha
Conjugated linoleic acids attenuate FSH- and IGF1-stimulated cell proliferation; IGF1, GATA4, and aromatase expression; and estradiol-17β production in buffalo granulosa cells involving PPARγ, PTEN, and PI3K/Akt. [electronic resource] - Reproduction (Cambridge, England) Sep 2012 - 373-83 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1741-7899
10.1530/REP-12-0079 doi
Animals
Aromatase--genetics
Buffaloes--metabolism
Cell Proliferation--drug effects
Cells, Cultured
Estradiol--biosynthesis
Female
Follicle Stimulating Hormone--pharmacology
GATA4 Transcription Factor--genetics
Gene Expression--drug effects
Granulosa Cells--cytology
Insulin-Like Growth Factor I--genetics
Linoleic Acids, Conjugated--pharmacology
PPAR gamma--physiology
PTEN Phosphohydrolase--antagonists & inhibitors
Phosphatidylinositol 3-Kinases--physiology
Phosphorylation--drug effects
Proto-Oncogene Proteins c-akt--physiology
RNA, Messenger--analysis
Signal Transduction--physiology
Conjugated linoleic acids attenuate FSH- and IGF1-stimulated cell proliferation; IGF1, GATA4, and aromatase expression; and estradiol-17β production in buffalo granulosa cells involving PPARγ, PTEN, and PI3K/Akt. [electronic resource] - Reproduction (Cambridge, England) Sep 2012 - 373-83 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1741-7899
10.1530/REP-12-0079 doi
Animals
Aromatase--genetics
Buffaloes--metabolism
Cell Proliferation--drug effects
Cells, Cultured
Estradiol--biosynthesis
Female
Follicle Stimulating Hormone--pharmacology
GATA4 Transcription Factor--genetics
Gene Expression--drug effects
Granulosa Cells--cytology
Insulin-Like Growth Factor I--genetics
Linoleic Acids, Conjugated--pharmacology
PPAR gamma--physiology
PTEN Phosphohydrolase--antagonists & inhibitors
Phosphatidylinositol 3-Kinases--physiology
Phosphorylation--drug effects
Proto-Oncogene Proteins c-akt--physiology
RNA, Messenger--analysis
Signal Transduction--physiology