Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome. [electronic resource]
Producer: 20130117Description: 4104-14 p. digitalISSN:- 1460-2083
- Abnormalities, Drug-Induced -- genetics
- Antigens, Differentiation -- genetics
- Basic Helix-Loop-Helix Transcription Factors -- genetics
- Cell Differentiation -- drug effects
- Cells, Cultured
- Embryonic Stem Cells -- metabolism
- Epigenesis, Genetic -- drug effects
- Eye Proteins -- genetics
- Histone Deacetylase Inhibitors -- pharmacology
- Histones -- metabolism
- Homeodomain Proteins -- genetics
- Humans
- Hydroxamic Acids -- pharmacology
- Methylation
- Nanog Homeobox Protein
- Neural Plate -- embryology
- Neural Stem Cells -- metabolism
- Neuroepithelial Cells -- metabolism
- Octamer Transcription Factor-3 -- genetics
- Oligonucleotide Array Sequence Analysis
- PAX6 Transcription Factor
- Paired Box Transcription Factors -- genetics
- Principal Component Analysis
- Promoter Regions, Genetic
- Protein Processing, Post-Translational
- Repressor Proteins -- genetics
- Transcription, Genetic
- Transcriptome
- Valproic Acid -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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