Therapeutic efficacy of silibinin on human neuroblastoma cells: Akt and NF-κB expressions may play an important role in silibinin-induced response. [electronic resource]
Producer: 20121120Description: 2053-63 p. digitalISSN:- 1573-6903
- Antineoplastic Agents
- Apoptosis -- drug effects
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Flow Cytometry
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Lethal Dose 50
- Matrix Metalloproteinase 2 -- metabolism
- Matrix Metalloproteinase 9 -- metabolism
- NF-kappa B -- biosynthesis
- Neuroblastoma -- drug therapy
- Oncogene Protein v-akt -- biosynthesis
- Protective Agents -- pharmacology
- Real-Time Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Silybin
- Silymarin -- pharmacology
- Tetrazolium Salts
- Thiazoles
- Transcription, Genetic -- drug effects
- Tumor Stem Cell Assay
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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