Therapeutic efficacy of silibinin on human neuroblastoma cells: Akt and NF-κB expressions may play an important role in silibinin-induced response.
Yousefi, Meysam
Therapeutic efficacy of silibinin on human neuroblastoma cells: Akt and NF-κB expressions may play an important role in silibinin-induced response. [electronic resource] - Neurochemical research Sep 2012 - 2053-63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1573-6903
10.1007/s11064-012-0827-9 doi
Antineoplastic Agents
Apoptosis--drug effects
Cell Cycle--drug effects
Cell Line, Tumor
Flow Cytometry
Gene Expression Regulation, Neoplastic--drug effects
Humans
Lethal Dose 50
Matrix Metalloproteinase 2--metabolism
Matrix Metalloproteinase 9--metabolism
NF-kappa B--biosynthesis
Neuroblastoma--drug therapy
Oncogene Protein v-akt--biosynthesis
Protective Agents--pharmacology
Real-Time Polymerase Chain Reaction
Signal Transduction--drug effects
Silybin
Silymarin--pharmacology
Tetrazolium Salts
Thiazoles
Transcription, Genetic--drug effects
Tumor Stem Cell Assay
Tumor Suppressor Protein p53--genetics
Therapeutic efficacy of silibinin on human neuroblastoma cells: Akt and NF-κB expressions may play an important role in silibinin-induced response. [electronic resource] - Neurochemical research Sep 2012 - 2053-63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1573-6903
10.1007/s11064-012-0827-9 doi
Antineoplastic Agents
Apoptosis--drug effects
Cell Cycle--drug effects
Cell Line, Tumor
Flow Cytometry
Gene Expression Regulation, Neoplastic--drug effects
Humans
Lethal Dose 50
Matrix Metalloproteinase 2--metabolism
Matrix Metalloproteinase 9--metabolism
NF-kappa B--biosynthesis
Neuroblastoma--drug therapy
Oncogene Protein v-akt--biosynthesis
Protective Agents--pharmacology
Real-Time Polymerase Chain Reaction
Signal Transduction--drug effects
Silybin
Silymarin--pharmacology
Tetrazolium Salts
Thiazoles
Transcription, Genetic--drug effects
Tumor Stem Cell Assay
Tumor Suppressor Protein p53--genetics