Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. [electronic resource]
Producer: 20120830Description: 1300-5 p. digitalISSN:- 1549-5477
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- Cell Cycle Proteins
- Cell Transformation, Neoplastic -- metabolism
- DNA-Binding Proteins -- genetics
- Genes, Dominant -- genetics
- HEK293 Cells
- Hepatomegaly -- metabolism
- Humans
- Liver -- drug effects
- Mice
- Mice, Transgenic
- Multiprotein Complexes -- metabolism
- Neurofibromin 2 -- metabolism
- Phenotype
- Phosphoproteins -- genetics
- Porphyrins -- pharmacology
- Protein Binding -- drug effects
- TEA Domain Transcription Factors
- Transcription Factors -- genetics
- Verteporfin
- YAP-Signaling Proteins
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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