Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP.

Liu-Chittenden, Yi

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. [electronic resource] - Genes & development Jun 2012 - 1300-5 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1549-5477

10.1101/gad.192856.112 doi


Adaptor Proteins, Signal Transducing--genetics
Animals
Cell Cycle Proteins
Cell Transformation, Neoplastic--metabolism
DNA-Binding Proteins--genetics
Genes, Dominant--genetics
HEK293 Cells
Hepatomegaly--metabolism
Humans
Liver--drug effects
Mice
Mice, Transgenic
Multiprotein Complexes--metabolism
Neurofibromin 2--metabolism
Phenotype
Phosphoproteins--genetics
Porphyrins--pharmacology
Protein Binding--drug effects
TEA Domain Transcription Factors
Transcription Factors--genetics
Verteporfin
YAP-Signaling Proteins