Structural insights into the catalytic active site and activity of human Nit2/ω-amidase: kinetic assay and molecular dynamics simulation. [electronic resource]
Producer: 20121011Description: 25715-26 p. digitalISSN:- 1083-351X
- Amino Acid Sequence
- Amino Acid Substitution
- Aminohydrolases -- biosynthesis
- Animals
- Asparagine -- analogs & derivatives
- Catalytic Domain
- Conserved Sequence
- Humans
- Hydrolysis
- Ketoglutaric Acids -- chemistry
- Kinetics
- Mice
- Molecular Dynamics Simulation
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Protein Binding
- Protein Structure, Quaternary
- Protein Structure, Secondary
- Recombinant Proteins -- biosynthesis
- Sequence Deletion
- Structural Homology, Protein
- Substrate Specificity
- Surface Properties
- Thermodynamics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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